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SMILES: ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=QNOKUAAIIQQOHF-MGPQQGTHSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340871   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 4


(Homo sapiens (Human))		BDBM340871
PNG
(US9765054, Compound 28G)
Show SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C16H13F3N2O2/c17-16(18,19)11-8-10(6-7-20-11)13-12(14(13)15(22)21-23)9-4-2-1-3-5-9/h1-8,12-14,23H,(H,21,22)/t12-,13-,14-/m1/s1
PDB
MMDB

KEGG

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PC cid
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US Patent
n/an/a 300n/an/an/an/an/an/a



CHDI Foundation, Inc.

US Patent


Assay Description
5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...

US Patent US9765054 (2017)


BindingDB Entry DOI: 10.7270/Q2XW4MZG
More data for this
Ligand-Target Pair