BDBM34091 benzamide derivative, 13s

SMILES: Nc1cc(F)c(Sc2nncs2)cc1C(=O)Nc1cccc(F)c1

InChI Key: InChIKey=FVKVMVBCHSSQQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM34091 (benzamide derivative, 13s) Show SMILES Nc1cc(F)c(Sc2nncs2)cc1C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C15H10F2N4OS2/c16-8-2-1-3-9(4-8)20-14(22)10-5-13(11(17)6-12(10)18)24-15-21-19-7-23-15/h1-7H,18H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institutes for Biological Sciences					Assay Description The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...				Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGM) (Oryctolagus cuniculus (rabbit))	BDBM34091 (benzamide derivative, 13s) Show SMILES Nc1cc(F)c(Sc2nncs2)cc1C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C15H10F2N4OS2/c16-8-2-1-3-9(4-8)20-14(22)10-5-13(11(17)6-12(10)18)24-15-21-19-7-23-15/h1-7H,18H2,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.36E+4	n/a	n/a	n/a	n/a	7.2	22
Shanghai Institutes for Biological Sciences					Assay Description The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...				Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0
					More data for this Ligand-Target Pair