BDBM340964 US9765054, Compound 106

SMILES: ONC(=O)[C@H]1[C@@H]([C@H]1c1ccccc1F)c1ccc(NCC(F)(F)F)nc1

InChI Key: InChIKey=QALRXRCESNFEEM-KFWWJZLASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 4 (Homo sapiens (Human))	BDBM340964 (US9765054, Compound 106) Show SMILES ONC(=O)[C@H]1[C@@H]([C@H]1c1ccccc1F)c1ccc(NCC(F)(F)F)nc1 Show InChI InChI=1S/C17H15F4N3O2/c18-11-4-2-1-3-10(11)14-13(15(14)16(25)24-26)9-5-6-12(22-7-9)23-8-17(19,20)21/h1-7,13-15,26H,8H2,(H,22,23)(H,24,25)/t13-,14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...				US Patent US9765054 (2017) BindingDB Entry DOI: 10.7270/Q2XW4MZG
					More data for this Ligand-Target Pair