BDBM34149 CHEMBL94422::N-benzenesulfonylgramine antagonist, 8

SMILES: CN(C)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=MHFSWNYVTLJUEH-UHFFFAOYSA-N

Data: 3 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 34149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34149 (CHEMBL94422 | N-benzenesulfonylgramine antagonist,...) Show SMILES CN(C)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18(2)12-14-13-19(17-11-7-6-10-16(14)17)22(20,21)15-8-4-3-5-9-15/h3-11,13H,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	-12.1	n/a	n/a	880	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34149 (CHEMBL94422 | N-benzenesulfonylgramine antagonist,...) Show SMILES CN(C)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18(2)12-14-13-19(17-11-7-6-10-16(14)17)22(20,21)15-8-4-3-5-9-15/h3-11,13H,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 6 receptor				J Med Chem 46: 2795-812 (2003) Article DOI: 10.1021/jm030030n BindingDB Entry DOI: 10.7270/Q2M0465F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34149 (CHEMBL94422 | N-benzenesulfonylgramine antagonist,...) Show SMILES CN(C)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18(2)12-14-13-19(17-11-7-6-10-16(14)17)22(20,21)15-8-4-3-5-9-15/h3-11,13H,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 6 receptor				Bioorg Med Chem Lett 13: 3355-9 (2003) BindingDB Entry DOI: 10.7270/Q2DN44GB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34149 (CHEMBL94422 | N-benzenesulfonylgramine antagonist,...) Show SMILES CN(C)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18(2)12-14-13-19(17-11-7-6-10-16(14)17)22(20,21)15-8-4-3-5-9-15/h3-11,13H,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonistic activity towards 5-hydroxytryptamine 6 receptor was evaluated in cAMP assay				J Med Chem 46: 2795-812 (2003) Article DOI: 10.1021/jm030030n BindingDB Entry DOI: 10.7270/Q2M0465F
					More data for this Ligand-Target Pair