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SMILES: CC(C)(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key: InChIKey=YFTZTNOZJQSECC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343686 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C20H22N4O2/c1-20(2,3)22-10-11-25-19-9-8-18-21-13-15(24(18)23-19)17-12-14-6-4-5-7-16(14)26-17/h4-9,12-13,22H,10-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343686 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C20H22N4O2/c1-20(2,3)22-10-11-25-19-9-8-18-21-13-15(24(18)23-19)17-12-14-6-4-5-7-16(14)26-17/h4-9,12-13,22H,10-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair