BDBM343691 3-(5-Chloro-1-benzofuran-2-yl)-6-{2-[(2S)-pyrrolidin-2-yl]ethoxy}imidazo[1,2-b]pyridazine::US9777004, 25

SMILES: Clc1ccc2oc(cc2c1)-c1cnc2ccc(OCC[C@@H]3CCCN3)nn12

InChI Key: InChIKey=YLHUDFFIQWPVDH-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM343691 (3-(5-Chloro-1-benzofuran-2-yl)-6-{2-[(2S)-pyrrolid...) Show SMILES Clc1ccc2oc(cc2c1)-c1cnc2ccc(OCC[C@@H]3CCCN3)nn12 |r| Show InChI InChI=1S/C20H19ClN4O2/c21-14-3-4-17-13(10-14)11-18(27-17)16-12-23-19-5-6-20(24-25(16)19)26-9-7-15-2-1-8-22-15/h3-6,10-12,15,22H,1-2,7-9H2/t15-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM343691 (3-(5-Chloro-1-benzofuran-2-yl)-6-{2-[(2S)-pyrrolid...) Show SMILES Clc1ccc2oc(cc2c1)-c1cnc2ccc(OCC[C@@H]3CCCN3)nn12 |r| Show InChI InChI=1S/C20H19ClN4O2/c21-14-3-4-17-13(10-14)11-18(27-17)16-12-23-19-5-6-20(24-25(16)19)26-9-7-15-2-1-8-22-15/h3-6,10-12,15,22H,1-2,7-9H2/t15-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair