BDBM343692 Formic acid-N-(2-{[3-(1-benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]oxy}-2-phenylethyl)propan-2-amine (1:1)::US9777004, 27

SMILES: CC(C)NCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1

InChI Key: InChIKey=SBJBNAJREHUALC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM343692 (Formic acid-N-(2-{[3-(1-benzofuran-2-yl)imidazo[1,...) Show SMILES CC(C)NCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 |w:6.5| Show InChI InChI=1S/C25H24N4O2/c1-17(2)26-16-23(18-8-4-3-5-9-18)31-25-13-12-24-27-15-20(29(24)28-25)22-14-19-10-6-7-11-21(19)30-22/h3-15,17,23,26H,16H2,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM343692 (Formic acid-N-(2-{[3-(1-benzofuran-2-yl)imidazo[1,...) Show SMILES CC(C)NCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 |w:6.5| Show InChI InChI=1S/C25H24N4O2/c1-17(2)26-16-23(18-8-4-3-5-9-18)31-25-13-12-24-27-15-20(29(24)28-25)22-14-19-10-6-7-11-21(19)30-22/h3-15,17,23,26H,16H2,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair