null
SMILES: Fc1ccc2oc(cc2c1)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12
InChI Key: InChIKey=XZVKEWCFFKMHPW-CQSZACIVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human)) | BDBM343699 (3-(5-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr... | US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human)) | BDBM343699 (3-(5-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr... | US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM | |||||||||||
More data for this Ligand-Target Pair |