BDBM343822 US9777008, Compound 116

SMILES: CN(CC(O)CN1CCc2ccccc2C1)c1cccc(CNC2CCOCC2)c1

InChI Key: InChIKey=CDGRGCNRTUXAGY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PRMT5/MEP50 Enzyme (Homo sapiens (Human))	BDBM343822 (US9777008, Compound 116) Show SMILES CN(CC(O)CN1CCc2ccccc2C1)c1cccc(CNC2CCOCC2)c1 Show InChI InChI=1S/C25H35N3O2/c1-27(18-25(29)19-28-12-9-21-6-2-3-7-22(21)17-28)24-8-4-5-20(15-24)16-26-23-10-13-30-14-11-23/h2-8,15,23,25-26,29H,9-14,16-19H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9777008 (2017) BindingDB Entry DOI: 10.7270/Q26975QQ
					More data for this Ligand-Target Pair