BDBM345862 US10202367, Compound 8

SMILES: CCN(CC)CCCCNC(=O)C1CCN(CC2N=C(OC2C)c2cc(OC)cc(OC)c2)CC1

InChI Key: InChIKey=XYPFWOMMRACPBR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)	BDBM345862 (US10202367, Compound 8) Show SMILES CCN(CC)CCCCNC(=O)C1CCN(CC2N=C(OC2C)c2cc(OC)cc(OC)c2)CC1 |c:18| Show InChI InChI=1S/C27H44N4O4/c1-6-30(7-2)13-9-8-12-28-26(32)21-10-14-31(15-11-21)19-25-20(3)35-27(29-25)22-16-23(33-4)18-24(17-22)34-5/h16-18,20-21,25H,6-15,19H2,1-5H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.55E+3	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas US Patent					Assay Description This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...				US Patent US10202367 (2019) BindingDB Entry DOI: 10.7270/Q23B6277
					More data for this Ligand-Target Pair