BDBM345890 US10202367, Compound 36

SMILES: CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1c2ccccc2cc2ccccc12

InChI Key: InChIKey=GQESQKOGNYWDGM-CFNAWJCCSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)	BDBM345890 (US10202367, Compound 36) Show SMILES CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1c2ccccc2cc2ccccc12 |r,c:3| Show InChI InChI=1S/C35H46N4O2/c1-24-19-25(2)22-39(21-24)16-8-15-36-34(40)27-13-17-38(18-14-27)23-32-26(3)41-35(37-32)33-30-11-6-4-9-28(30)20-29-10-5-7-12-31(29)33/h4-7,9-12,20,24-27,32H,8,13-19,21-23H2,1-3H3,(H,36,40)/t24-,25+,26?,32?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	214	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas US Patent					Assay Description This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...				US Patent US10202367 (2019) BindingDB Entry DOI: 10.7270/Q23B6277
					More data for this Ligand-Target Pair