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SMILES: CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1c(Cl)cccc1C(F)(F)F

InChI Key: InChIKey=UAZCJLUWVGQDEP-IDMBRNPXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345898   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus genotype 2a (isolate HC-J6) (HCV...)		BDBM345898
PNG
(US10202367, Compound 44)
Show SMILES CC1OC(=NC1CN1CCC(CC1)C(=O)NCCCN1C[C@@H](C)C[C@@H](C)C1)c1c(Cl)cccc1C(F)(F)F |r,c:3|
Show InChI InChI=1S/C28H40ClF3N4O2/c1-18-14-19(2)16-36(15-18)11-5-10-33-26(37)21-8-12-35(13-9-21)17-24-20(3)38-27(34-24)25-22(28(30,31)32)6-4-7-23(25)29/h4,6-7,18-21,24H,5,8-17H2,1-3H3,(H,33,37)/t18-,19+,20?,24?
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 354n/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Kansas

US Patent


Assay Description
This example demonstrates the EC50 and CC50 values against HCV according to the HCVcc-RLuc reporter assay described in Example 5 and the cytotoxicity...

US Patent US10202367 (2019)


BindingDB Entry DOI: 10.7270/Q23B6277
More data for this
Ligand-Target Pair