BDBM346017 3-[5-Methyl-6-(4- pyridin-3-yl-thiazol- 2-ylamino)-1H- benzoimidazol-2-yl]- benzonitrile::US10202370, Example 010

SMILES: Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cccc(c1)C#N

InChI Key: InChIKey=NROVXTRLZBPRKE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346017 (3-[5-Methyl-6-(4- pyridin-3-yl-thiazol- 2-ylamino)...) Show SMILES Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cccc(c1)C#N Show InChI InChI=1S/C23H16N6S/c1-14-8-19-20(27-22(26-19)16-5-2-4-15(9-16)11-24)10-18(14)28-23-29-21(13-30-23)17-6-3-7-25-12-17/h2-10,12-13H,1H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair