BDBM346020 US10202370, Example 024::[6-Methyl-2-(3- piperidin-1-ylmethyl- 5-trifluoromethyl- phenyl)-3H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cc(CN2CCCCC2)cc(c1)C(F)(F)F

InChI Key: InChIKey=YCCZMOACTVGCIF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346020 (US10202370, Example 024 | [6-Methyl-2-(3- piperidi...) Show SMILES Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cc(CN2CCCCC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C29H27F3N6S/c1-18-10-24-25(14-23(18)36-28-37-26(17-39-28)20-6-5-7-33-15-20)35-27(34-24)21-11-19(12-22(13-21)29(30,31)32)16-38-8-3-2-4-9-38/h5-7,10-15,17H,2-4,8-9,16H2,1H3,(H,34,35)(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
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