BDBM346062 US10202370, Example 100::[2-(3-Difluoromethyl- phenyl)-1-isopropyl- 6-methyl-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)F

InChI Key: InChIKey=PIOAHFWWENRHTB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346062 (US10202370, Example 100 | [2-(3-Difluoromethyl- ph...) Show SMILES CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)F Show InChI InChI=1S/C26H23F2N5S/c1-15(2)33-23-11-16(3)20(31-26-32-22(14-34-26)17-7-9-29-10-8-17)13-21(23)30-25(33)19-6-4-5-18(12-19)24(27)28/h4-15,24H,1-3H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair