null

SMILES: CC(=O)Nc1cc(ccn1)-c1cnc(C)c2n(ccc12)S(=O)(=O)c1ccc(F)cc1F

InChI Key: InChIKey=PFOLVPHIPLCVLH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM346199 (US10202373, Compound I-11 | US10202373, Example 3C) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c2n(ccc12)S(=O)(=O)c1ccc(F)cc1F Show InChI InChI=1S/C21H16F2N4O3S/c1-12-21-16(17(11-25-12)14-5-7-24-20(9-14)26-13(2)28)6-8-27(21)31(29,30)19-4-3-15(22)10-18(19)23/h3-11H,1-2H3,(H,24,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
MILLENNIUM PHARMACEUTICALS, INC. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US10202373 (2019) BindingDB Entry DOI: 10.7270/Q2FN18BC
					More data for this Ligand-Target Pair