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SMILES: COC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(C)(=O)=O

InChI Key: InChIKey=IMODIMPXDVBSKY-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346215   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))		BDBM346215
PNG
(US10202373, Compound I-29 | US10202373, Example 4A)
Show SMILES COC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C15H14N4O4S/c1-23-15(20)18-14-7-10(3-5-17-14)12-8-16-9-13-11(12)4-6-19(13)24(2,21)22/h3-9H,1-2H3,(H,17,18,20)
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US Patent
n/an/a 30n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...

US Patent US10202373 (2019)


BindingDB Entry DOI: 10.7270/Q2FN18BC
More data for this
Ligand-Target Pair