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SMILES: COC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(=O)(=O)C1CC1

InChI Key: InChIKey=XMHAVEXGTPFWSO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM346216 (US10202373, Compound I-30 | US10202373, Example 4H) Show SMILES COC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(=O)(=O)C1CC1 Show InChI InChI=1S/C17H16N4O4S/c1-25-17(22)20-16-8-11(4-6-19-16)14-9-18-10-15-13(14)5-7-21(15)26(23,24)12-2-3-12/h4-10,12H,2-3H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
MILLENNIUM PHARMACEUTICALS, INC. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US10202373 (2019) BindingDB Entry DOI: 10.7270/Q2FN18BC
					More data for this Ligand-Target Pair