BDBM346235 US10202373, Compound I-49::US10202373, Example 14
SMILES: O=S(=O)(C1CC1)n1ccc2c(cncc12)-c1ccnc(Nc2ccncn2)c1
InChI Key: InChIKey=UCHBHGDVYBBOMC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human)) | BDBM346235 (US10202373, Compound I-49 | US10202373, Example 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
MILLENNIUM PHARMACEUTICALS, INC. US Patent | Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro... | US Patent US10202373 (2019) BindingDB Entry DOI: 10.7270/Q2FN18BC | |||||||||||
More data for this Ligand-Target Pair |