BDBM346255 2-[4-(2-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 18

SMILES: Cn1nccc1-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12

InChI Key: InChIKey=IHWUNRITCVVDFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Mus musculus)	BDBM346255 (2-[4-(2-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin...) Show SMILES Cn1nccc1-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12 Show InChI InChI=1S/C21H17N9O/c1-29-17(4-6-27-29)20-15-5-9-30(21(15)26-13-25-20)12-19(31)28-18-3-2-14(10-24-18)16-11-22-7-8-23-16/h2-11,13H,12H2,1H3,(H,24,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair