BDBM346258 N-(5-pyrazin-2-yl-2-pyridyl)-2-[4-[2-(trifluoromethyl)-4-pyridyl]pyrrolo[2,3-d]pyrimidin-7-yl]acetamide::US10202375, Example 21

SMILES: FC(F)(F)c1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12

InChI Key: InChIKey=OFVZKOSLNUNKOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Mus musculus)	BDBM346258 (N-(5-pyrazin-2-yl-2-pyridyl)-2-[4-[2-(trifluoromet...) Show SMILES FC(F)(F)c1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12 Show InChI InChI=1S/C23H15F3N8O/c24-23(25,26)18-9-14(3-5-29-18)21-16-4-8-34(22(16)32-13-31-21)12-20(35)33-19-2-1-15(10-30-19)17-11-27-6-7-28-17/h1-11,13H,12H2,(H,30,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair