BDBM346979 US10202379, Reference Example 719

SMILES: C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(Cl)cccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=HMEGFDJAJTUOND-XCLFUZPHSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346979 (US10202379, Reference Example 719) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(Cl)cccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H21ClF3N3O4S/c1-13(25(27,28)29)30-12-32(31-9-14(10-33)22(34)23(35)21(31)24(30)36)20-15-6-4-7-18(26)17(15)11-37-19-8-3-2-5-16(19)20/h2-9,13,20,33,35H,10-12H2,1H3/t13-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.36	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346979 (US10202379, Reference Example 719) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(Cl)cccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H21ClF3N3O4S/c1-13(25(27,28)29)30-12-32(31-9-14(10-33)22(34)23(35)21(31)24(30)36)20-15-6-4-7-18(26)17(15)11-37-19-8-3-2-5-16(19)20/h2-9,13,20,33,35H,10-12H2,1H3/t13-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair