BDBM347063 US10202390, Example 18

SMILES: CCCn1cc(nn1)-c1cnc(cc1NC1CC1)-c1cnc2cc(cnn12)C#N

InChI Key: InChIKey=JDHXZJLBUNAELN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347063 (US10202390, Example 18) Show SMILES CCCn1cc(nn1)-c1cnc(cc1NC1CC1)-c1cnc2cc(cnn12)C#N Show InChI InChI=1S/C20H19N9/c1-2-5-28-12-18(26-27-28)15-10-22-17(7-16(15)25-14-3-4-14)19-11-23-20-6-13(8-21)9-24-29(19)20/h6-7,9-12,14H,2-5H2,1H3,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair