BDBM347243 US10202404, Compound C-18

SMILES: CN1Cn2cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C(=O)N1C

InChI Key: InChIKey=ARSCYGPSLIYTMG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM347243 (US10202404, Compound C-18) Show SMILES CN1Cn2cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C(=O)N1C Show InChI InChI=1S/C18H15F2N5O3S/c1-23-8-25-7-11(15(26)16(27)14(25)18(28)24(23)2)17-22-21-13(29-17)5-9-3-4-10(19)6-12(9)20/h3-4,6-7,27H,5,8H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Previously, a series of two-fold dilution on test samples were carried out in a 96-well plate (50 μL/well). Two plates were made for measuring a...				US Patent US10202404 (2019) BindingDB Entry DOI: 10.7270/Q2WQ05WN
					More data for this Ligand-Target Pair