BDBM347265 US10202411, Compound 327
SMILES: Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CF)[C@H]1O
InChI Key:
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein [S283T] (Hepatitis C virus genotype 1b (isolate Japanese) (...) | BDBM347265 (US10202411, Compound 327) | PDB MMDB B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC US Patent | Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac... | US Patent US10202411 (2019) BindingDB Entry DOI: 10.7270/Q2RX9F67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM347265 (US10202411, Compound 327) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC US Patent | Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac... | US Patent US10202411 (2019) BindingDB Entry DOI: 10.7270/Q2RX9F67 | |||||||||||
More data for this Ligand-Target Pair |