BDBM347523 4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)-2-methoxypyridine::US9790201, 9

SMILES: COc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F

InChI Key: InChIKey=FAWJXWUBPKOQHL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347523 (4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...) Show SMILES COc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C19H18ClF3N2O2/c1-27-17-9-12(6-7-24-17)18(26)25-8-2-3-13(11-25)15-5-4-14(20)10-16(15)19(21,22)23/h4-7,9-10,13H,2-3,8,11H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair