BDBM347527 N,N-Dimethyl-4-{[3-(3-methylphenyl)piperidin-1-yl]carbonyl}pyridin-2-amine::US9790201, 13

SMILES: CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1cccc(C)c1

InChI Key: InChIKey=UODSIZRSALBPHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347527 (N,N-Dimethyl-4-{[3-(3-methylphenyl)piperidin-1-yl]...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1cccc(C)c1 Show InChI InChI=1S/C20H25N3O/c1-15-6-4-7-16(12-15)18-8-5-11-23(14-18)20(24)17-9-10-21-19(13-17)22(2)3/h4,6-7,9-10,12-13,18H,5,8,11,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair