BDBM347530 4-{[3-(4-Chlorophenyl)piperidin-1-yl]carbonyl}-N,N-dimethylpyridin-2-amine::US9790201, 16

SMILES: CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1

InChI Key: InChIKey=GVULCCISMRYXKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347530 (4-{[3-(4-Chlorophenyl)piperidin-1-yl]carbonyl}-N,N...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H22ClN3O/c1-22(2)18-12-15(9-10-21-18)19(24)23-11-3-4-16(13-23)14-5-7-17(20)8-6-14/h5-10,12,16H,3-4,11,13H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair