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SMILES: Cc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1

InChI Key: InChIKey=CBGIUSFDDIMJNK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347535   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM347535
PNG
(2-(Azetidin-1-yl)-4-{[3-(4-methylphenyl)piperidin-...)
Show SMILES Cc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1
Show InChI InChI=1S/C21H25N3O/c1-16-5-7-17(8-6-16)19-4-2-11-24(15-19)21(25)18-9-10-22-20(14-18)23-12-3-13-23/h5-10,14,19H,2-4,11-13,15H2,1H3
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.20E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...

US Patent US9790201 (2017)


BindingDB Entry DOI: 10.7270/Q2377BVZ
More data for this
Ligand-Target Pair