BDBM347536 2-(Azetidin-1-yl)-4-{[3-(4-chlorophenyl)piperidin-1-yl]carbonyl}pyridine::US9790201, 22

SMILES: Clc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1

InChI Key: InChIKey=SQDQUNQOCNGGOU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347536 (2-(Azetidin-1-yl)-4-{[3-(4-chlorophenyl)piperidin-...) Show SMILES Clc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1 Show InChI InChI=1S/C20H22ClN3O/c21-18-6-4-15(5-7-18)17-3-1-10-24(14-17)20(25)16-8-9-22-19(13-16)23-11-2-12-23/h4-9,13,17H,1-3,10-12,14H2	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair