BDBM347545 4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carbonyl}-N-methylpyridin-2-amine::US9790201, 31

SMILES: CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C

InChI Key: InChIKey=DIEIDVSSVGUXTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347545 (4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C19H22ClN3O/c1-13-10-16(20)5-6-17(13)15-4-3-9-23(12-15)19(24)14-7-8-22-18(11-14)21-2/h5-8,10-11,15H,3-4,9,12H2,1-2H3,(H,21,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair