BDBM347555 1-(4-{[3-(4-Methylphenyl)piperidin-1-yl]carbonyl}pyridin-2-yl)azetidin-3-ol::US9790201, 41

SMILES: Cc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N1CC(O)C1

InChI Key: InChIKey=SVIJMSCNICNPMQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347555 (1-(4-{[3-(4-Methylphenyl)piperidin-1-yl]carbonyl}p...) Show SMILES Cc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N1CC(O)C1 Show InChI InChI=1S/C21H25N3O2/c1-15-4-6-16(7-5-15)18-3-2-10-23(12-18)21(26)17-8-9-22-20(11-17)24-13-19(25)14-24/h4-9,11,18-19,25H,2-3,10,12-14H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair