BDBM347558 N,N-Dimethyl-4-({3-[4-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)pyridin-2-amine formate::US9790201, 44

SMILES: CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=HCMOGSHNHJGXKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347558 (N,N-Dimethyl-4-({3-[4-(trifluoromethyl)phenyl]pipe...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H22F3N3O/c1-25(2)18-12-15(9-10-24-18)19(27)26-11-3-4-16(13-26)14-5-7-17(8-6-14)20(21,22)23/h5-10,12,16H,3-4,11,13H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair