BDBM347568 N-Methyl-4-({3-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)pyridin-2-amine::US9790201, 54

SMILES: CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=GEFRPRVZPYVTIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347568 (N-Methyl-4-({3-[2-(trifluoromethyl)phenyl]piperidi...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H20F3N3O/c1-23-17-11-13(8-9-24-17)18(26)25-10-4-5-14(12-25)15-6-2-3-7-16(15)19(20,21)22/h2-3,6-9,11,14H,4-5,10,12H2,1H3,(H,23,24)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair