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SMILES: CNc1cc(cnn1)C(=O)N1CCC[C@H](C1)c1ccc(Cl)cc1C

InChI Key: InChIKey=RCEOZLLSTSTGHE-CYBMUJFWSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347587   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM347587
PNG
(5-{[(3S)-3-(4-Chloro-2-methylphenyl)piperidin-1-yl...)
Show SMILES CNc1cc(cnn1)C(=O)N1CCC[C@H](C1)c1ccc(Cl)cc1C
Show InChI InChI=1S/C18H21ClN4O/c1-12-8-15(19)5-6-16(12)13-4-3-7-23(11-13)18(24)14-9-17(20-2)22-21-10-14/h5-6,8-10,13H,3-4,7,11H2,1-2H3,(H,20,22)/t13-/m1/s1
MMDB

NCI pathway
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.18E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...

US Patent US9790201 (2017)


BindingDB Entry DOI: 10.7270/Q2377BVZ
More data for this
Ligand-Target Pair