BDBM347593 5-({3-[2-Methoxy-4-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)-N-methylpyridazin-3-amine::US9790201, 78

SMILES: CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(cc1OC)C(F)(F)F

InChI Key: InChIKey=BOBJLXWUZNOPBO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347593 (5-({3-[2-Methoxy-4-(trifluoromethyl)phenyl]piperid...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(cc1OC)C(F)(F)F Show InChI InChI=1S/C19H21F3N4O2/c1-23-17-8-13(10-24-25-17)18(27)26-7-3-4-12(11-26)15-6-5-14(19(20,21)22)9-16(15)28-2/h5-6,8-10,12H,3-4,7,11H2,1-2H3,(H,23,25)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair