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SMILES: COc1ccc(C2CCCN(C2)C(=O)c2cnnc(c2)N(C)C)c(C)c1

InChI Key: InChIKey=TVDWIFBRAXXBFW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347595   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM347595
PNG
(5-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...)
Show SMILES COc1ccc(C2CCCN(C2)C(=O)c2cnnc(c2)N(C)C)c(C)c1
Show InChI InChI=1S/C20H26N4O2/c1-14-10-17(26-4)7-8-18(14)15-6-5-9-24(13-15)20(25)16-11-19(23(2)3)22-21-12-16/h7-8,10-12,15H,5-6,9,13H2,1-4H3
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
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US Patent
n/an/a 160n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...

US Patent US9790201 (2017)


BindingDB Entry DOI: 10.7270/Q2377BVZ
More data for this
Ligand-Target Pair