BDBM347599 5-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carbonyl}-N,N-dimethylpyridazin-3-amine::US9790201, 84

SMILES: CCOc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(c1)N(C)C

InChI Key: InChIKey=VVDWPGWMIPNCSB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347599 (5-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...) Show SMILES CCOc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(c1)N(C)C Show InChI InChI=1S/C20H25ClN4O2/c1-4-27-18-11-16(21)7-8-17(18)14-6-5-9-25(13-14)20(26)15-10-19(24(2)3)23-22-12-15/h7-8,10-12,14H,4-6,9,13H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair