BDBM347613 3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1-ethyl-1H-pyrazol-4-yl)carbonyl]piperidine::US9790201, 98

SMILES: CCn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F

InChI Key: InChIKey=OIHLQUXYPDJQPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347613 (3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1-ethyl...) Show SMILES CCn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C18H19ClF3N3O/c1-2-25-11-13(9-23-25)17(26)24-7-3-4-12(10-24)15-6-5-14(19)8-16(15)18(20,21)22/h5-6,8-9,11-12H,2-4,7,10H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
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