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SMILES: COc1ccc(C2CCCN(C2)C(=O)c2cn(C)nc2C)c(C)c1

InChI Key: InChIKey=ZRXBDYXIROULMD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347616   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM347616
PNG
(1-[(1,3-Dimethyl-1H-pyrazol-4-yl)carbonyl]-3-(4-me...)
Show SMILES COc1ccc(C2CCCN(C2)C(=O)c2cn(C)nc2C)c(C)c1
Show InChI InChI=1S/C19H25N3O2/c1-13-10-16(24-4)7-8-17(13)15-6-5-9-22(11-15)19(23)18-12-21(3)20-14(18)2/h7-8,10,12,15H,5-6,9,11H2,1-4H3
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.03E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...

US Patent US9790201 (2017)


BindingDB Entry DOI: 10.7270/Q2377BVZ
More data for this
Ligand-Target Pair