BDBM347618 3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1,3-dimethyl-1H-pyrazol-4-yl)carbonyl]piperidine::US9790201, 103

SMILES: Cc1nn(C)cc1C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F

InChI Key: InChIKey=ILOGNYNMGMWFMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347618 (3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1,3-dim...) Show SMILES Cc1nn(C)cc1C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C18H19ClF3N3O/c1-11-15(10-24(2)23-11)17(26)25-7-3-4-12(9-25)14-6-5-13(19)8-16(14)18(20,21)22/h5-6,8,10,12H,3-4,7,9H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair