BDBM347625 4-{[3-(4-Methoxyphenyl)azepan-1-yl]carbonyl}-N-methylpyridin-2-amine::US9790201, 110

SMILES: CNc1cc(ccn1)C(=O)N1CCCCC(C1)c1ccc(OC)cc1

InChI Key: InChIKey=UKZAVGYTVVWEKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347625 (4-{[3-(4-Methoxyphenyl)azepan-1-yl]carbonyl}-N-met...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCCC(C1)c1ccc(OC)cc1 Show InChI InChI=1S/C20H25N3O2/c1-21-19-13-16(10-11-22-19)20(24)23-12-4-3-5-17(14-23)15-6-8-18(25-2)9-7-15/h6-11,13,17H,3-5,12,14H2,1-2H3,(H,21,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair