null

SMILES: CCN(CC)c1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12

InChI Key: InChIKey=HLHDWOQYFQCFHT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 348149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM348149 (US9790228, Compound 68) Show SMILES CCN(CC)c1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C25H24FN7O/c1-3-32(4-2)24-17(9-15-7-5-6-8-20(15)30-24)13-33-25-21(23(27)28-14-29-25)22(31-33)16-10-18(26)12-19(34)11-16/h5-12,14,34H,3-4,13H2,1-2H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM348149 (US9790228, Compound 68) Show SMILES CCN(CC)c1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C25H24FN7O/c1-3-32(4-2)24-17(9-15-7-5-6-8-20(15)30-24)13-33-25-21(23(27)28-14-29-25)22(31-33)16-10-18(26)12-19(34)11-16/h5-12,14,34H,3-4,13H2,1-2H3,(H2,27,28,29)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM348149 (US9790228, Compound 68) Show SMILES CCN(CC)c1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C25H24FN7O/c1-3-32(4-2)24-17(9-15-7-5-6-8-20(15)30-24)13-33-25-21(23(27)28-14-29-25)22(31-33)16-10-18(26)12-19(34)11-16/h5-12,14,34H,3-4,13H2,1-2H3,(H2,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM348149 (US9790228, Compound 68) Show SMILES CCN(CC)c1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C25H24FN7O/c1-3-32(4-2)24-17(9-15-7-5-6-8-20(15)30-24)13-33-25-21(23(27)28-14-29-25)22(31-33)16-10-18(26)12-19(34)11-16/h5-12,14,34H,3-4,13H2,1-2H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair