BDBM349750 2-[(4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(4,5-dimethyl-4H-1,2,4-triazol-3-yl)methyl]-1H-benzimidazole-6-carboxylic acid::US10208019, Example 10A-20

SMILES: Cc1nnc(Cn2c(CN3CCC(CC3)c3cccc(OCc4ccc(Cl)cc4F)n3)nc3ccc(cc23)C(O)=O)n1C

InChI Key: InChIKey=RUIZMSHNGSKZPO-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM349750 (2-[(4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridin-2-y...) Show SMILES Cc1nnc(Cn2c(CN3CCC(CC3)c3cccc(OCc4ccc(Cl)cc4F)n3)nc3ccc(cc23)C(O)=O)n1C Show InChI InChI=1S/C31H31ClFN7O3/c1-19-36-37-29(38(19)2)17-40-27-14-21(31(41)42)7-9-26(27)34-28(40)16-39-12-10-20(11-13-39)25-4-3-5-30(35-25)43-18-22-6-8-23(32)15-24(22)33/h3-9,14-15,20H,10-13,16-18H2,1-2H3,(H,41,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...				US Patent US10208019 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S4X
					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM349750 (2-[(4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridin-2-y...) Show SMILES Cc1nnc(Cn2c(CN3CCC(CC3)c3cccc(OCc4ccc(Cl)cc4F)n3)nc3ccc(cc23)C(O)=O)n1C Show InChI InChI=1S/C31H31ClFN7O3/c1-19-36-37-29(38(19)2)17-40-27-14-21(31(41)42)7-9-26(27)34-28(40)16-39-12-10-20(11-13-39)25-4-3-5-30(35-25)43-18-22-6-8-23(32)15-24(22)33/h3-9,14-15,20H,10-13,16-18H2,1-2H3,(H,41,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...				US Patent US10208019 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S4X
					More data for this Ligand-Target Pair