null

SMILES: COCCn1c(cc2c1-c1ccncc1OC21CCOCC1)C(N)=O

InChI Key: InChIKey=IQJKHKMDUAVVBY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C/Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM350260 (US10208056, Compound 87) Show SMILES COCCn1c(cc2c1-c1ccncc1OC21CCOCC1)C(N)=O Show InChI InChI=1S/C18H21N3O4/c1-23-9-6-21-14(17(19)22)10-13-16(21)12-2-5-20-11-15(12)25-18(13)3-7-24-8-4-18/h2,5,10-11H,3-4,6-9H2,1H3,(H2,19,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.2	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM350260 (US10208056, Compound 87) Show SMILES COCCn1c(cc2c1-c1ccncc1OC21CCOCC1)C(N)=O Show InChI InChI=1S/C18H21N3O4/c1-23-9-6-21-14(17(19)22)10-13-16(21)12-2-5-20-11-15(12)25-18(13)3-7-24-8-4-18/h2,5,10-11H,3-4,6-9H2,1H3,(H2,19,22)	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350260 (US10208056, Compound 87) Show SMILES COCCn1c(cc2c1-c1ccncc1OC21CCOCC1)C(N)=O Show InChI InChI=1S/C18H21N3O4/c1-23-9-6-21-14(17(19)22)10-13-16(21)12-2-5-20-11-15(12)25-18(13)3-7-24-8-4-18/h2,5,10-11H,3-4,6-9H2,1H3,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair