BindingDB logo
myBDB logout

BDBM350267 US10208056, Compound 95

SMILES: CCn1c(cc2[C@@H](Oc3cnccc3-c12)C1CCOCC1)C(N)=O

InChI Key: InChIKey=MDUVEFOUGGEOCI-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350267   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CDK8/Cyclin C


(Homo sapiens (Human))		BDBM350267
PNG
(US10208056, Compound 95)
Show SMILES CCn1c(cc2[C@@H](Oc3cnccc3-c12)C1CCOCC1)C(N)=O |r|
Show InChI InChI=1S/C18H21N3O3/c1-2-21-14(18(19)22)9-13-16(21)12-3-6-20-10-15(12)24-17(13)11-4-7-23-8-5-11/h3,6,9-11,17H,2,4-5,7-8H2,1H3,(H2,19,22)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1.41n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair