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SMILES: FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccc(Cl)cc3)cccc2n1

InChI Key: InChIKey=UAXZOCYIZZRAEU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350366   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM350366
PNG
(US9802904, 17)
Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccc(Cl)cc3)cccc2n1
Show InChI InChI=1S/C28H19ClF3N3/c29-21-14-12-20(13-15-21)19-10-8-18(9-11-19)16-33-25-6-3-7-26-23(25)17-34-27(35-26)22-4-1-2-5-24(22)28(30,31)32/h1-15,17,33H,16H2
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.20E+3n/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware

US Patent


Assay Description
This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...

US Patent US9802904 (2017)


BindingDB Entry DOI: 10.7270/Q2TF00H8
More data for this
Ligand-Target Pair