BDBM350379 US9802904, 53

SMILES: CC(C)c1ccccc1-c1nc2CCCc2c(NCc2ccc(cc2)-c2ccccc2)n1

InChI Key: InChIKey=JYVLYJIAQDHTHL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
USP1/UAF1 (Homo sapiens (Human))	BDBM350379 (US9802904, 53) Show SMILES CC(C)c1ccccc1-c1nc2CCCc2c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C29H29N3/c1-20(2)24-11-6-7-12-25(24)29-31-27-14-8-13-26(27)28(32-29)30-19-21-15-17-23(18-16-21)22-9-4-3-5-10-22/h3-7,9-12,15-18,20H,8,13-14,19H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair