BDBM350830 US9795602, Compound 59
SMILES: CN1[C@@H]2CCCC[C@@H]2n2cc(C(=O)NCc3c(F)cc(F)cc3F)c(=O)c(O)c2C1=O
InChI Key: InChIKey=UVUKPPFFIJYRQM-CVEARBPZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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POU domain, class 2, transcription factor 2 (Homo sapiens (Human)) | BDBM350830 (US9795602, Compound 59) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GILEAD SCIENCES, INC. US Patent | Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an... | US Patent US9795602 (2017) BindingDB Entry DOI: 10.7270/Q2K35WTB | |||||||||||
More data for this Ligand-Target Pair |