BDBM350835 US9795602, Compound 25b
SMILES: [H][C@]12CCO[C@@]1([H])N(CC)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)c(Cl)c1F
InChI Key: InChIKey=QQBCAEHXIZCVBO-FKIZINRSSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Octamer-binding transcription factor 2 (OCT2) (Homo sapiens (Human)) | BDBM350835 (US9795602, Compound 25b) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GILEAD SCIENCES, INC. US Patent | Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an... | US Patent US9795602 (2017) BindingDB Entry DOI: 10.7270/Q2K35WTB | |||||||||||
More data for this Ligand-Target Pair |